Molecular Diagnostics and Therapeutics (20 credits)
Code | School | Level | Credits | Semesters |
LIFE3130 | Life Sciences | 3 | 20 | Autumn UK |
- Code
- LIFE3130
- School
- Life Sciences
- Level
- 3
- Credits
- 20
- Semesters
- Autumn UK
Summary
This module covers the application of various biochemical and molecular biology-based techniques employed in clinical diagnosis, as well as the most recent development in molecular therapies. This will help students to develop an understanding of modern biochemical and molecular diagnostics and of the development of new molecular therapies. This module will involve diagnostic and therapeutic approaches such as:
- biochemical assay for clinical testing
- the use of antibodies as biochemical reagents
- proteomics analysis using mass spectrometry
- gene expression measurements using qRT PCR
- immunodetection of protein in cells and tissues
- RNA sequencing and quantification
- miRNA and CRISPR-mediated gene editing
- Therapeutic targeting of pathological proteins and protein aggregates
- Exosomes and drug re-purposing
- Gene therapy and the use of adeno associated viruses
- immunotherapy and small molecule-drugs
- the human microbiome as new therapeutic target
Target Students
Available to all students registered for a Single Honours degree in Biochemistry with or without another subject. Available to JYA/Erasmus students. Students from other degree courses need the module convenors’ permission in writing to select this module and may be removed from the enrolment without this.
Classes
This module may be delivered through lectures, seminars, workshops and labs etc
Assessment
- 50% Coursework: Essay (1,500 words).
- 50% Exam (1-hour): Examsys based exam
Assessed by end of designated period
Educational Aims
To develop an understanding of modern biochemical and molecular diagnostics. To develop an understanding of methods for the development of new molecular therapies.Learning Outcomes
Understand the scientific basis behind a variety of molecular medical diagnostics
Understand the scientific basis behind the development of novel molecular medical therapies
Appreciate and be conversant with the methodology available
Understand the limitations of the technology