The Genome and Human Disease
| Code | School | Level | Credits | Semesters |
| LIFE2072 | Life Sciences | 2 | 20 | Autumn UK |
- Code
- LIFE2072
- School
- Life Sciences
- Level
- 2
- Credits
- 20
- Semesters
- Autumn UK
Summary
There are a limited number of places on this module. Students are reminded that enrolments which are not agreed by the offering school in advance may be cancelled without notice. The module will start with an examination of the structure and function of the eukaryotic genome and progress to consider the links between changes to the genome and human disease. Key techniques for studying the genome and disease will also be presented in a series of sessions at intervals throughout the module.
Target Students
Biology U6UBOLGY/U7UBOLGY (C100/C101); Zoology U6UZOLGY/U7UZOLGY (C300/C301); Genetics U6UGNTCS/U7UGNTCS (C400/C401); Tropical BiologyU6UTRPBY (C190); Natural Sciences U6UNATRS/U7UNATRS (FGC0/GFC0).
Classes
This module may be delivered through lectures, seminars, workshops and labs etc
Assessment
- 10% Coursework 1: Assessment of practical work.
- 90% Exam 1 (2-hour): ExamSys exam.
Assessed by end of autumn semester
Educational Aims
The module will start with an examination of the structure and function of the eukaryotic genome and progress to consider the links between changes to the genome and human disease. Key techniques for studying the genome and disease will also be presented in a series of sessions at intervals throughout the module.Learning Outcomes
After completion of the module students should be able to:
- Discuss the structure and function of eukaryotic genomes, including the human genome
- Explain the molecular organization of key genetic elements and the experimental approaches that led to this understanding
- Analyse the potential of current techniques to manipulate genes and genomes and identify their limitations
- Describe the study of medical genetics and evaluate the impact of recent technological advances on disease gene identification
- Summarise specific disease examples which illustrate linkage mapping, mutation identification and different types of DNA mutation
- Perform the experimental techniques required to sub-clone DNA fragments into expression vectors
- Interpret the results of basic experiments in molecular genetics and summarise their outcomes.
- Approach problem solving in a creative and innovative manner