Synthesis and Spectroscopy (Part B) [Apprenticeship]
| Code | School | Level | Credits | Semesters |
| CHEM2026 | Chemistry | 2 | 10 | Full Year UK |
- Code
- CHEM2026
- School
- Chemistry
- Level
- 2
- Credits
- 10
- Semesters
- Full Year UK
Summary
• Synthesis, reactivity, bonding and conformation of rings, stereoelectronic effects, anomeric effect, introduction to carbohydrates. Synthesis of rings including cycloadditions. Enantioselectivity, diastereoselectivity, prochirality etc. Use of cyclic transitions states to predict stereochemical reaction outcome.
• Carbon-carbon bond forming reactions and the influence of heteroatoms on reactivity. Revise carbonyl reactions (aldol, Claisen etc). Sulfur including reactivity of dithianes, oxidation levels, rearrangements etc. Silicon as a protecting group, electronic effects on reactivity, Peterson reaction etc. Phosphorus including reagent preparation, Arbuzov, P(III) vs P(V), ylides, Wittig/HWE, stereochemical outcome, Staudinger reduction. Boron including hydroboration; Lewis acidity and allylation of carbonyls etc.
Target Students
BSc Hons Chemistry with Industry or Level 6 Laboratory Scientist Apprentices.
Classes
This module contains: 34 hours of e-learning material and self-directed study (including 1 hour of exam preparation Q&A with 1 hour preparation time); 2 hours of vidcons; 2 hours of tutorials (with 2 hours preparation time); 2 hours of workshops; 1 hour of seminar (with 1 hour preparation time), 4 hours for coursework. The lecture material is self-directed online study, with points throughout the year at which certain topics should be completed. This is to meet with timetabled vidcons, tutorials, workshops and seminars as part of the blended learning approach. The tutorials, workshops and seminars take place during on campus visit weeks, while the vidcons will be online via Microsoft Teams while apprentices are at employer sites.
Assessment
- 25% Coursework 1: Written coursework submission.
- 25% Coursework 2: Written coursework submission.
- 50% Exam 1 (1-hour): Second re-assessment: If a further re-assessment is allowed by satisfying the conditions of Undergraduate Course Regulation 19, the form of the further re-assessment for this module will be 100% coursework.
Assessed by end of designated period
Educational Aims
• Imbue understanding and appreciation of organic stereochemistry and related topics, including conformation analysis and the fundamental origins of stereocontrol in organic reactions.• Underpin this with an understanding of a variety of spectroscopic techniques and how they may be chosen to provide the maximum amount of information about structure and bonding.Learning Outcomes
• Recognise functional groups and anticipate their reactivity.
• Explain reactions using appropriate curly arrow mechanisms and diagrams.
• Apply principles of retrosynthetic analysis & plan synthesis of target molecules.
• Choose and discuss reactions and communicate understanding of reactivity.
• Predict and explain conformations of organic molecules.
• Predict impact of stereochemistry on reactivity.
• Transferable Skills: Problem Solving; Written Communication Skills.
Elements of the following knowledge, skills and behaviours will be built upon in this module:
K1 The underlying scientific principles, principal theories, concepts and terminology of laboratory based experimentation, including laboratory techniques relevant to the specialist discipline.
K2 The ways in which advanced science and technology is developed, established techniques of scientific enquiry and research methodologies.
K3 The theoretical basis for application of the science relevant to one specialist discipline including how to apply this during experimental design and implementation of research programmes.
S11 Identify and use the scientific approaches appropriate to one specialist discipline required to solve problems, support new investigations and follow-up experiments in the laboratory.
S14 Work autonomously to analyse, interpret and evaluate scientific data and present the results of laboratory work and problem solving clearly and concisely in written and oral form.
B26 Manages time effectively, being able to plan and complete work to schedule.