Bioprocessing and Bioengineering
Code | School | Level | Credits | Semesters |
BIOS4124 | Biosciences | 4 | 20 | Spring UK |
- Code
- BIOS4124
- School
- Biosciences
- Level
- 4
- Credits
- 20
- Semesters
- Spring UK
Summary
The module content includes recombinant protein expression, purification of proteins and advanced aspects such as metabolic engineering. Current trends in bio-processing technologies include an overview of microbial gene expression and of novel biomolecules including challenges in the scale up of different production processes exemplified through theory and practice. Novel algal expression systems give an insight into developing futuristic technologies.
Target Students
Only available for students studying MSc Biotechnology.
Classes
Blended learning approach including lectures, practicals, tutorials and student-centred learning.
Assessment
- 40% Coursework 1: Practical Report.
- 60% Exam 1 (2-hour): In-person exam.
Assessed by end of spring semester
Educational Aims
The aim of this module is to build fundamental knowledge and skills in the utilisation of biological systems in biomanufacturing and bioconversions. Students will learn biological science applied to the exploitation of living systems and their components. The aim of the students is also to understand prokaryotic and eukaryotic protein expression with examples and their application to biotech industries.Learning Outcomes
1. Understand the advanced aspects of gene expression and protein synthesis in microbes.
2. Examples of developments in microbial processes: use of microorganisms to synthesise recombinant proteins, bulk chemicals, therapeutics.
3. Gain practical experience in protein expression and purification.
4. Understand different types of fedbatch and batch bioprocesses.
5. Apply fundamental scientific principles to bioprocesses and understand the limitations of current practice.
6. Understand processes for the successful scale up of bioreactions.
7. Be aware of research and developments in relevant technologies and their potential impact on current practice.
8. Be able to design, implement and document practical procedures.